(Last modified 13.2.2008)
PixelProstate (new version 3.0):
The cancer area of the prostate is outlined
on the histological slide. Using pathologist's visual memory an identical
tumour area is painted with the mouse on the virtual slide (Figure 1). Total
prostate volume is calculated using the ellipsoidal method: 4/3 x pi x
(length/2 x width/2 x height/2). The corresponding cancer area and volume are
computed using the Red-Green-Blue-values (RGB) of the virtual slides: prostate
is painted cyan with the RGB value of 0,255,255 and the cancer area purple with
the RGB value of 128,0,128. The tumour volume is the sum of each cancer area
multiplied by the thickness of the average slice. The total tumour volume and
percentage of cancer in the entire specimen are then calculated. A 3D picture
is automatically generated (Figure 2). The picture can be rotated in two
different magnifications. This is a useful feature for clinicians wishing to
compare the morphological and ultrasound findings. A report can be produced
containing a summary of the calculations and 3D pictures (Figure 3). A video
recording of the results is possible ("on the fly"). Send the video
recordig to your client by email! All the digitized material can be saved using
strong encryption for later usage e.g. at clinical meetings. No camera or other
special equipment is needed. PP-program runs on a standard MS Windows
workstation. See also: J.Nickels. PixelProstate - a simple software program
for the measurement of prostate cancer volume. (The definitive version is
available at)Histopathology
2007; 50; 519-521.
Download a 30 day trial version:PixelProstate
trial (admin account not needed) or
PixelProstate
trial (with setup/install + uninstall)(0,8 Mb).
Figure 1. Painting the cancer area.
Fig 3. Report of the findings.
